Indiana Requirements at a Glance
Practice Authority
An Indiana APRN functions in an expanded nursing role at a specialized level and makes independent decisions about the nursing needs of clients. To be granted prescriptive authority, the APRN must practice in collaboration with a licensed physician, as evidenced by a written practice agreement.
Nurse practitioners are one of Indiana’s APRN categories, alongside certified nurse-midwives, clinical nurse specialists, and certified registered nurse anesthetists.
Physician-to-APC Provider Ratio Cap
None. Indiana law does not set a maximum number of APRNs with whom a physician may enter into practice agreements. However, the APRN’s application for prescriptive authority must list all other written practice agreements of both the physician and the APRN.
Chart Review Requirements
The practice agreement must describe the time and manner of the physician’s review of the APRN’s prescribing practices, including a requirement that the APRN submit documentation of prescribing practices to the physician within seven days, with at least a 5% random sampling of the charts and medications prescribed.
Meeting Requirements
None. Indiana law does not set specific meeting requirements for physicians and APRNs who are parties to a practice agreement.
Geographic Requirements
No fixed mileage or proximity standard, but the practice agreement must address how the physician and APRN will maintain geographic proximity. The term “geographic proximity” is not defined.
Prescriptive/Delegation Authority Agreement
A written practice agreement. At minimum, it must include:
- Names, home and business addresses, and phone numbers of the APRN and physician
- All other offices or locations where the APRN is authorized to prescribe
- All specialty or board certifications of both parties
- The specific manner of collaboration: how you will work together, share practice trends and responsibilities, maintain geographic proximity, and provide coverage during the physician’s absence, incapacity, infirmity, or emergency
- Any limits the physician places on the APRN’s prescriptive authority
- The time and manner of the physician’s prescribing review (see Chart Review Requirements)
- A list of all other written practice agreements of either party
- The duration of the agreement
APRN applicants must draft and submit an individualized collaborative practice agreement to the Board. The Board publishes a sample agreement.
Amendments and termination: the APRN must immediately notify the Board in writing of any change to the agreement (including changes to the collaborating physician’s prescriptive authority) and of any termination, by removing, canceling, or rescinding the agreement on the Board’s website.
Audits: before December 31 of each even-numbered year, the Indiana Professional Licensing Agency randomly audits at least 1% (but not more than 10%) of APRN practice agreements for compliance with Board requirements.
Physician Collaboration Eligibility Requirements
A collaborating physician in Indiana must:
- Be licensed in Indiana to be a party to a practice agreement
- Hold an active, unrestricted license. The agreement terminates automatically if either the APRN or the physician no longer does.
DEA Requirements / Application Process
Prescriptive authority application: the APRN submits to the Board an application under oath, the required fees, proof of Indiana RN licensure (or a compact-state RN license with a filed Multi-State Privilege Notification Form), proof of a baccalaureate or higher degree in nursing, proof of a graduate-level pharmacology course of at least two (2) semester hours, proof of meeting all requirements for APRN practice in Indiana, and proof of the collaborative practice agreement.
Once approved, the Board sends written notice of prescriptive authority with an identification number and authorized initials. Each prescription must carry the APRN’s signature, credential initials, and identification number, and electronic-prescribing requirements apply.
Controlled substances: the APRN must also obtain an Indiana controlled substances registration and a federal DEA registration.
Renewal: APRN licensure and prescriptive authority both renew every two years. Renewal requires an application, a current signed and dated collaborative practice agreement, the fee, and thirty (30) contact hours of continuing education, at least eight in pharmacology.
Boards, Trade Associations & Authoritative Links
Indiana State Board of Nursing — Collaborative Practice Agreement Requirement
Indiana State Board of Nursing — Add/Remove/Update Collaborative Practice
Board Sample Collaborative Practice Agreement (APRN Prescriptive Authority)
848 IAC 5 (Prescriptive Authority for Advanced Practice Registered Nurses)
Disclaimer: This page for general informational purposes only and is not legal or medical advice. Indiana requirements are set by state law and board rule and may change; consult your own counsel before relying on this information. CollabDocs facilitates physician-APC introductions and does not practice medicine or guarantee outcomes except as stated in a signed services agreement.
Reviewed by the CollabDocs Compliance Team | Last reviewed October 19, 2026
Indiana Requirements at a Glance
Practice Authority
An Indiana APRN functions in an expanded nursing role at a specialized level and makes independent decisions about the nursing needs of clients. To be granted prescriptive authority, the APRN must practice in collaboration with a licensed physician, as evidenced by a written practice agreement.
Nurse practitioners are one of Indiana’s APRN categories, alongside certified nurse-midwives, clinical nurse specialists, and certified registered nurse anesthetists.
Physician-to-APC Provider Ratio Cap
None. Indiana law does not set a maximum number of APRNs with whom a physician may enter into practice agreements. However, the APRN’s application for prescriptive authority must list all other written practice agreements of both the physician and the APRN.
Chart Review Requirements
The practice agreement must describe the time and manner of the physician’s review of the APRN’s prescribing practices, including a requirement that the APRN submit documentation of prescribing practices to the physician within seven days, with at least a 5% random sampling of the charts and medications prescribed.
Meeting Requirements
None. Indiana law does not set specific meeting requirements for physicians and APRNs who are parties to a practice agreement.
Geographic Requirements
No fixed mileage or proximity standard, but the practice agreement must address how the physician and APRN will maintain geographic proximity. The term “geographic proximity” is not defined.
Prescriptive/Delegation Authority Agreement
A written practice agreement. At minimum, it must include:
- Names, home and business addresses, and phone numbers of the APRN and physician
- All other offices or locations where the APRN is authorized to prescribe
- All specialty or board certifications of both parties
- The specific manner of collaboration: how you will work together, share practice trends and responsibilities, maintain geographic proximity, and provide coverage during the physician’s absence, incapacity, infirmity, or emergency
- Any limits the physician places on the APRN’s prescriptive authority
- The time and manner of the physician’s prescribing review (see Chart Review Requirements)
- A list of all other written practice agreements of either party
- The duration of the agreement
APRN applicants must draft and submit an individualized collaborative practice agreement to the Board. The Board publishes a sample agreement.
Amendments and termination: the APRN must immediately notify the Board in writing of any change to the agreement (including changes to the collaborating physician’s prescriptive authority) and of any termination, by removing, canceling, or rescinding the agreement on the Board’s website.
Audits: before December 31 of each even-numbered year, the Indiana Professional Licensing Agency randomly audits at least 1% (but not more than 10%) of APRN practice agreements for compliance with Board requirements.
Physician Collaboration Eligibility Requirements
A collaborating physician in Indiana must:
- Be licensed in Indiana to be a party to a practice agreement
- Hold an active, unrestricted license. The agreement terminates automatically if either the APRN or the physician no longer does.
DEA Requirements / Application Process
Prescriptive authority application: the APRN submits to the Board an application under oath, the required fees, proof of Indiana RN licensure (or a compact-state RN license with a filed Multi-State Privilege Notification Form), proof of a baccalaureate or higher degree in nursing, proof of a graduate-level pharmacology course of at least two (2) semester hours, proof of meeting all requirements for APRN practice in Indiana, and proof of the collaborative practice agreement.
Once approved, the Board sends written notice of prescriptive authority with an identification number and authorized initials. Each prescription must carry the APRN’s signature, credential initials, and identification number, and electronic-prescribing requirements apply.
Controlled substances: the APRN must also obtain an Indiana controlled substances registration and a federal DEA registration.
Renewal: APRN licensure and prescriptive authority both renew every two years. Renewal requires an application, a current signed and dated collaborative practice agreement, the fee, and thirty (30) contact hours of continuing education, at least eight in pharmacology.
Boards, Trade Associations & Authoritative Links
Indiana State Board of Nursing — Collaborative Practice Agreement Requirement
Indiana State Board of Nursing — Add/Remove/Update Collaborative Practice
Board Sample Collaborative Practice Agreement (APRN Prescriptive Authority)
848 IAC 5 (Prescriptive Authority for Advanced Practice Registered Nurses)
Disclaimer: This page for general informational purposes only and is not legal or medical advice. Indiana requirements are set by state law and board rule and may change; consult your own counsel before relying on this information. CollabDocs facilitates physician-APC introductions and does not practice medicine or guarantee outcomes except as stated in a signed services agreement.
Reviewed by the CollabDocs Compliance Team | Last reviewed October 19, 2026
